Mohsen Yoosefzadeh Najafabadi

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Education:
B.Sc. University of Tehran;
M.Sc. University of Tehran;
PhD. University of Guelph
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Dr. Mohsen Yoosefzadeh-Najafabadi is an Assistant Professor of Dry Bean Breeding and Computational Biology at the University of Guelph. His research integrates plant breeding, quantitative genetics, artificial intelligence, multi-omics, digital phenotyping, and climate-scenario modelling to accelerate the development of resilient, high-yielding dry bean cultivars for Ontario and beyond. He earned his PhD at the University of Guelph with a focus on soybean genetics and big-data breeding approaches and has since broadened his work across legumes and other crops. His program operates at the intersection of breeding and computation, developing next-generation tools, AI-based pipelines, and multi-omics frameworks to address complex agricultural challenges related to yield, stress resilience, nutritional quality, and canning performance.
“My program aims to develop dry bean cultivars that deliver meaningful value to growers, processors, and the broader agri-food system. By integrating high-throughput technologies, AI-driven analytics, and multi-omics insights, we try to create cultivars that are resilient, high-performing, and aligned with the future needs of agriculture.”
Areas of Research Interest
Dry Bean Breeding & Genetics
Designing breeding strategies for high-yield, stress-resilient, and quality-optimized dry bean cultivars across multiple market classes.
AI-Driven & Computational Plant Breeding
Integrating hybrid AI, predictive AI, generative AI, rule-based modelling, reasonable learning, and large-scale data fusion to enable next-generation breeding pipelines.
Omics-Based Selection & Multi-Omics Integration
Connecting genomics, phenomics, metabolomics, enviromics, and transcriptomics to accelerate selection accuracy and biological discovery.
Remote Sensing & Phenomics
Deploying UAV, field-based, satellite, and proximal imaging systems to model complex traits and build predictive phenomic tools.
Genome–Phenome Relationships Across Omics Layers
Studying genome–proteome–phenome–envirome to understand trait architecture, stress responses, and epigenetic mechanisms.
Computational Tools & AI Platforms
Creator of BeanGPT, AllInOne Pre-processing, and multi-omics R/Shiny platforms for plant breeding, phenotyping, and predictive agriculture.
Courses
Graduate
- PLNT*6520 – Applied Computational Biology in Agricultural Science
Winter Semester – A graduate-level course integrating AI, multi-omics, and computational tools for modern crop improvement.
Undergraduate
- MBG*2400 – Fundamentals of Plant & Animal Genetics
Fall Semester - This course introduces students to the foundational principles of heredity in plants and animals.
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Selected Publications:
Yoosefzadeh-Najafabadi, SA Jackson. (2025). Hybrid AI in synthetic biology: next era in agriculture. Trends in Plant Science.
Yoosefzadeh-Najafabadi, M. (2025). Merging traditional practices and modern technology through computational plant breeding. Plant Physiology 199 (1).
Yoosefzadeh-Najafabadi, M. (2025). From Text to Traits: Exploring the Role of Large Language Models in Plant Breeding. Frontiers in Plant Science 16, 1583344.
Yoosefzadeh-Najafabadi, M., Xavier, A., Eskandari, M., Hesami, M. (2025). Machine learning after a decade: is it still a missing keystone in genomic-based plant breeding?. Artificial Intelligence Review 58 (9), 260.
Hesami, M., Yoosefzadeh-Najafabadi, M. (2025). Trends in production, consumption, trade, and research of dry beans across the globe and Canada. Canadian Journal of Plant Science 105, 1-14.
Yoosefzadeh-Najafabadi, M., Lukens, L., & Costa-Neto, G. (2024). Integrated Omics Approaches to Accelerate Plant Improvement. Frontiers in plant science. 15:1397582.
Yoosefzadeh-Najafabadi, M., Torabi, S., Tulpan, D., Rajcan, I., & Eskandari, M. (2023). Application of SVR-Mediated GWAS for Identification of Durable Genetic Regions Associated with Soybean Seed Quality Traits. Plants. 12(14):2659.
Yoosefzadeh-Najafabadi, M., Heidari, A., & Rajcan, I. (2023). AllInOne Pre-Processing: A Comprehensive Preprocessing Framework in Plant Field Phenotyping. SoftwareX Journal. 101464.
Yoosefzadeh-Najafabadi, M., Pourreza, A., Singh, K., Sandhu, K., Adak, A., Eskandari, M., Murray, S., & Rajcan, I. (2023). Remote and Proximal Sensing: How Far Has It Come to Help Plant Breeders?. Advances in Agronomy.
Yoosefzadeh-Najafabadi, M., Hesami, M., & Eskandari, M. (2023). Machine Learning-assisted approaches in modernized plant breeding programs. Genes. 14, 4, 777.
Yoosefzadeh-Najafabadi, M., & Rajcan, I. (2022). Six Decades of Soybean Breeding in Ontario, Canada: A Tradition of Innovation. Canadian Journal of Plant Science, 0008-4220.
Yoosefzadeh-Najafabadi, M., Rajcan, I., & Mahsa Vazin (2022). High-Throughput Plant Breeding Approaches: Moving Along with Plant-Based Food Demands for Pet Food Industries. Frontiers in Veterinary Science. 1467.
Yoosefzadeh-Najafabadi, M., Rajcan, I., & Eskandari, M. (2022). Optimizing Genomic Selection in Soybean: An Important Improvement in Agricultural Genomics. Heliyon. e11873.
Yoosefzadeh-Najafabadi, M., Torabi, S., Torkamaneh, D., Rajcan, I., & Eskandari, M. (2022). Machine Learning based Genome-Wide Association Studies for Uncovering QTL Underlying Soybean Yield and its Components. International Journal of Molecular Science, 23(10), 5538.
